clinical trials
Clinical trials, research and surveys are open until the quota of participants is met or the study is concluded. We are consistently checking and updating this page. If you come across a study that is closed or no longer accepting participants, please let us know here.
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It is the responsibility of each of us with HS to participate in whatever studies, research and surveys possible to further the research and knowledge of HS for ourselves, friends and other warriors currently suffering and those who haven't yet been diagnosed.
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**Attention Researchers, Physicians, Pharmaceutical Reps or Sponsors**
If you are interested in listing your clinical trial, please contact us here.
"PARTICIPATE LIKE THE FUTURE OF HS DEPENDS ON IT, BECAUSE IT DOES."
**30 MINUTE ONLNE SURVEY**
NO GEOGRAPHIC LIMITATIONS
Participants must be 18 years of age, able to communicate in English and have an HS diagnosis from a health care provider.
Reconstructions w/ Back Donor Site Flaps & Validation of Quality of Life Scales
The latissimus dorsi flap is the oldest and most used technique for breast reconstruction. Nonetheless, there are few studies evaluation the long-term effect of harvesting one of the muscles of the back. NCT04526561
Interdisciplinary Care Compared to
Usual Care
The overall aim of this study is to determine the effectiveness of an interdisciplinary combined clinic intervention compared to usual care in a population of patients with two or more Immune-mediated inflammatory diseases (IMIDs). NCT04200690
Effect of Sclerotherapy on Fistulas and Sinus Tracts in HS
This study evaluates the effect of hypertonic saline 23.4% injection in fistulas or sinus tracts in adult patients with hidradenitis suppurativa. NCT02805595
5-year Longitudinal Observational Study of Patients Undergoing Therapy for IMISC (TARGET-DERM)
TARGET-DERM will create a research registry of patients with IMISC within academic and community real-world practices in order to assess the safety and effectiveness of current and future therapies. NCT03661866
Cutaneous and Circulating Inflammatory Biomarkers
Correlate cellular/molecular changes in blood (cells and serum), and tissue, with clinical/histopathological phenotypes. NCT04440410
Efficacy and Safety of INCB054707
To evaluate the efficacy and safety of INCB054707 in participants with hidradenitis suppurativa over a 16-week placebo-controlled treatment period followed by a 36 -week open-label extension period. NCT04476043
LY3041658 in Adults With Hidradenitis Suppurativa
The reason for this study is to see if the study drug LY3041658 is effective in participants with moderate-to-severe hidradenitis suppurativa (HS). NCT04493502
Efficacy and Safety of Two Secukinumab Dose Regimens
Assess the safety and tolerability of secukinumab. NCT 03713619
Observational Registry & Biospecimen Repository
Aims to comprehensively characterize the clinical and biological features. The results will provide a basis for the development of a clinical classification system and identification of potential treatments for HS. ***AGE 10 AND UP*** NCT04115566
Tofacitinib for Immune Skin Conditions in Down Syndrome
Evaluates the safety and efficacy treatment with Tofacitinib known to block IFN signaling, in adults with DS and an autoimmune and/or autoinflammatory skin condition. NCT04246372
Repeat Doses of CSL324 with HS and Palmoplantar Pustulosis
CSL324 is a novel, recombinant therapy that may treat diseases caused by increased numbers of neutrophils at sites of inflammation. NCT03972280
Safety and Efficacy of 3 kinase inhibitors
Study with 3 kinase inhibitors (PF 06650833, PF 06700841 and PF 06826647) in participants with moderate to severe HS. NCT04092452
Long-Term Safety and Effectiveness of Humira
Evaluate the long-term safety and effectiveness of Humira in patients with HS in real-world clinical practice in Japan. NCT03894956
Oral Upadacitinib Tablet Compared to Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa to Assess Change in Disease Symptoms. NCT04430855
The purpose of the study is to test the efficacy and safety of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS).
NCT04242498
Negative Pressure Wound Therapy
Evaluate the use of Negative Pressure Wound Therapy with instillation, which has potential to allow early wound coverage as an alternative. NCT04325607
HIDRAWEAR - *Clinicians Only*
US and Europe
HidraWear is a 3-part wound care kit that enables quick and easy dressing placement and adhesive free, secure retention in difficult to dress areas, in this case the axilla.
Who is StuffThatWorks and what do they do? Read more below. We are hoping do much more collaborating with them to help the HS community! You can take the Living through Covid-19 times with HS Survey too!
Wound Dressings for HS University of Miami
How types of wound dressings affect quality of life for people with HS. NCT04194541
Ohio State University Oral Health and Modifiable Risk Factors with HS
A survey studying what dietary or environmental changes might improve symptoms for patients affected by hidradenitis suppurativa. NCT03146676
University of California, San Francisco (UCSF)COVID-19 REGISTRY
If you, or your caregiver have tested and confirmed positive for COVID-19 with HS, please complete the REGISTRY here.
Complement C5a Receptors in Hidradenitis Suppurativa
To study the role of C5a in Hidradenitis Suppurativa (HS). Complement C5a is a major chemotactic factor that stimulates neutrophil infiltration. NCT04251663
Wound Care Trial in Ireland
Open to anyone in Ireland.
Volunteers are needed for a wound care clinical trial. HS warriors are needed to participate in this trial for HS wound dressing of the armpits.
Study of Efficacy & Safety of Investigational Treatments in Patients With Moderate toSevere HS
**PARTICIPANTS NEEDED**
The main purpose of this study is to assess preliminary efficacy and safety of CFZ533 and LYS006 in patients with moderate to severe hidradenitis suppurativa and to determine if CFZ533 and LYS006 have an adequate clinical profile for further clinical development. NCT3527798
Treatment of Hidradenitis Suppurativa With Eth 755nm Alexandrite Laser
**TRIAL EXTENDED**
Patients with bilateral hidradenitis in the axilla, groin and/or inframammary will be treated on one side with the Alexandrite hair removal laser. The other side will serve as the control. NCT03054155
Low Dose Radiotherapy for Advanced Hidradenitis Suppurativa (RTHS)
**TRIAL EXTENDED**
To establish the safety of radiotherapy in the treatment of advanced hidradenitis suppurativa. Patients will receive radiotherapy treatment over one week and then will be followed for the next three months. NCT03040804
Battlefield Acupuncture for Pain
Investigate battlefield acupuncture as a treatment for the pain of hidradenitis suppurativa. NCT04218422
Wound Etiology and Healing Study (WE-HEAL)
**EVERYONE SHOULD PARTICIPATE**
The purpose of the WE-HEAL Study is to help researchers use human tissue samples and records to study the reasons why some heal quickly and some have problems healing wounds. All patients seen with an open wound or HS are invited to participate. NCT01352078
Impact of Hidradenitis Suppurativa on Quality of Life Functions
**EVERYONE SHOULD PARTICIPATE**
The goal of this study is to get a better understanding of the impact of Hidradenitis Suppurativa (HS) on the quality of life of patients with this condition. Study participation will last for 1 day, with potential for follow-up in the future. NCT03288337
Molecular Biology and Genetics of Hidradenitis Suppurativa
**PARTICIPANTS NEEDED**
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Analysis of Gene expression and microbiome profiling in hidradenitis suppurativa to identify immunological biomarkers of disease activity.
Treatment of Hidradenitis Suppurativa With Eth 755nm Alexandrite Laser
**TRIAL EXTENDED**
Patients with bilateral hidradenitis in the axilla, groin and/or inframammary will be treated on one side with the Alexandrite hair removal laser. The other side will serve as the control. NCT03054155
Epidermal Barrier Function With
Anti-Oxidant Defense Mechanisms in Skin Conditions
**PARTICIPANTS NEEDED**
Samples of skin and blood of patients with chronic skin conditions (including HS) to study the expression of anti-oxidative enzymes, skin barrier proteins and inflammatory molecules. NCT03198390
National Registry For Patients With HS
**PEVERYONE SHOULD PARTICIPATE PEDIATRIC AND ADULT**
5 year study for adult and pediatric HS patients. Various States. Click below for info. NCT03289585
**PARTICIPANTS NEEDED**
5 year study for adult and pediatric HS patients. Various States. Click below for info.
**PARTICIPANTS NEEDED**
57 LOCATIONS INTERNATIONALLY
WITH RECRUITMENT UNDERWAY
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To evaluate the safety and efficacy of 2 dose levels of risankizumab in adult participants with moderate to severe Hidradenitis Suppurativa (HS). NCT03926169
Bimekizumab for Moderate to Severe Hidradenitis Suppurativa
(BE HEARD I)
The purpose of the study is to evaluate the efficacy and safety of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS). NCT04242446
Bimekizumab for Moderate to Severe Hidradenitis Suppurativa (BE HEARD II)
The purpose of the study is to test the efficacy and safety of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS). NCT04242498
Review all FDA trials here.
See all UK clinical trials here.