clinical trials

Clinical trials, research and surveys are open until the quota of participants is met or the study is concluded.  We are consistently checking and updating this page.  If you come across a study that is closed or no longer accepting participants, please let us know here.

It is the responsibility of each of us with HS to participate in whatever studies, research and surveys possible to further the research and knowledge of HS for ourselves, friends and other warriors currently suffering and those who haven't yet been diagnosed.

**Attention Researchers, Physicians, Pharmaceutical Reps or Sponsors**

If you are interested in listing your clinical trial, please contact us here.


Study of Efficacy and Safety of Investigational Treatments

Assess preliminary efficacy and safety of CFZ533 and LYS006. NCT03827798

Testing a Body-functionality Intervention for Body Image in Individuals With Skin Conditions

Global online HS study (written study).  NO GEOGRAPHIC LIMITATIONS.  Anyone over the age 18 can participate. NCT04445974

Reconstructions w/ Back Donor Site Flaps & Validation of Quality of Life Scales

The latissimus dorsi flap is the oldest and most used technique for breast reconstruction. Nonetheless, there are few studies evaluation the long-term effect of harvesting one of the muscles of the back. NCT04526561

HS Body Study Survey



Participants must be 18 years of age, able to communicate in English and have an HS diagnosis from a health care provider.

Cutaneous and Circulating Inflammatory Biomarkers 

Correlate cellular/molecular changes in blood (cells and serum), and tissue, with clinical/histopathological phenotypes. NCT04440410

Interdisciplinary Care Compared to

Usual Care 

The overall aim of this study is to determine the effectiveness of an interdisciplinary combined clinic intervention compared to usual care in a population of patients with two or more Immune-mediated inflammatory diseases (IMIDs). NCT04200690

Effect of Sclerotherapy on Fistulas and Sinus Tracts in HS

This study evaluates the effect of hypertonic saline 23.4% injection in fistulas or sinus tracts in adult patients with hidradenitis suppurativa. NCT02805595

5-year Longitudinal Observational Study of Patients Undergoing Therapy for IMISC (TARGET-DERM)

TARGET-DERM will create a research registry of patients with IMISC within academic and community real-world practices in order to assess the safety and effectiveness of current and future therapies. NCT03661866

Efficacy and Safety of Two Secukinumab Dose Regimens

Assess the safety and tolerability of secukinumab.  NCT 03713619

Efficacy and Safety of INCB054707

To evaluate the efficacy and safety of INCB054707 in participants with hidradenitis suppurativa over a 16-week placebo-controlled treatment period followed by a 36 -week open-label extension period. NCT04476043

LY3041658 in Adults With Hidradenitis Suppurativa

The reason for this study is to see if the study drug LY3041658 is effective in participants with moderate-to-severe hidradenitis suppurativa (HS). NCT04493502

Repeat Doses of CSL324 with HS and Palmoplantar Pustulosis

CSL324 is a novel, recombinant therapy that may treat diseases caused by increased numbers of neutrophils at sites of inflammation. NCT03972280

Observational Registry & Biospecimen Repository

Aims to comprehensively characterize the clinical and biological features. The results  will provide a basis for the development of a clinical classification system and identification of potential treatments for HS.  ***AGE 10 AND UP*** NCT04115566

Tofacitinib for Immune Skin Conditions in Down Syndrome

Evaluates the safety and efficacy treatment with Tofacitinib known to block IFN signaling, in adults with DS and an autoimmune and/or autoinflammatory skin condition. NCT04246372


Who is StuffThatWorks and what do they do?  Read more below.  We are hoping do much more collaborating with them to help the HS community!  You can take the Living through Covid-19 times with HS Survey too!

Safety and Efficacy of 3 kinase inhibitors

Study with 3 kinase inhibitors (PF 06650833, PF 06700841 and PF 06826647) in participants with moderate to severe HS.  NCT04092452

Long-Term Safety and Effectiveness of Humira

Evaluate the long-term safety and effectiveness of Humira in patients with HS in real-world clinical practice in Japan.  NCT03894956

HIDRAWEAR - *Clinicians Only*

US and Europe

HidraWear is a 3-part wound care kit that enables quick and easy dressing placement and adhesive free, secure retention in difficult to dress areas, in this case the axilla.

The purpose of the study is to test the efficacy and safety of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS).


Negative Pressure Wound Therapy 

Evaluate the use of Negative Pressure Wound Therapy with instillation, which has potential to allow early wound coverage as an alternative. NCT04325607

Battlefield Acupuncture for Pain 

Investigate battlefield acupuncture as a treatment for the pain of hidradenitis suppurativa.  NCT04218422

Wound Etiology and Healing Study (WE-HEAL)


 The purpose of the WE-HEAL Study is to help researchers use human tissue samples and records to study the reasons why some  heal quickly and some have problems healing wounds. All patients seen with an open wound or HS are invited to participate.  NCT01352078

Wound Dressings for HS University of Miami

How types of wound dressings affect quality of life for people with HS. NCT04194541

Ohio State University Oral Health and Modifiable Risk Factors with HS

A survey studying what dietary or environmental changes might improve symptoms for patients affected by hidradenitis suppurativa. NCT03146676

University of California, San Francisco (UCSF)COVID-19 REGISTRY 

If you, or your caregiver have tested and confirmed positive for COVID-19 with HS, please complete the REGISTRY here.

Complement C5a Receptors in Hidradenitis Suppurativa

To study the role of C5a in Hidradenitis Suppurativa (HS). Complement C5a is a major chemotactic factor that stimulates neutrophil infiltration.  NCT04251663

Wound Care Trial in Ireland

Open to anyone in Ireland. 


Volunteers are needed for a wound care clinical trial. HS warriors are needed to participate in this trial for HS wound dressing of the armpits.

Study of Efficacy & Safety of Investigational Treatments in Patients With Moderate toSevere HS


 The main purpose of this study is to assess preliminary efficacy and safety of CFZ533 and LYS006 in patients with moderate to severe hidradenitis suppurativa and to determine if CFZ533 and LYS006 have an adequate clinical profile for further clinical development. NCT3527798

Treatment of Hidradenitis Suppurativa With Eth 755nm Alexandrite Laser


 Patients with bilateral hidradenitis in the axilla, groin and/or inframammary will be treated on one side with the Alexandrite hair removal laser. The other side will serve as the control. NCT03054155

Impact of Hidradenitis Suppurativa on Quality of Life Functions


 The goal of this study is to get a better understanding of the impact of Hidradenitis Suppurativa (HS) on the quality of life of patients with this condition.  Study participation will last for 1 day, with potential for follow-up in the future. NCT03288337

Bimekizumab for Moderate to Severe Hidradenitis Suppurativa


The purpose of the study is to evaluate the efficacy and safety of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS). NCT04242446

Bimekizumab for Moderate to Severe Hidradenitis Suppurativa (BE HEARD II)

The purpose of the study is to test the efficacy and safety of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS). NCT04242498

Epidermal Barrier Function With

Anti-Oxidant Defense Mechanisms in Skin Conditions


 Samples of skin and blood of patients with chronic skin conditions (including HS) to study the expression of anti-oxidative enzymes, skin barrier proteins and inflammatory molecules.  NCT03198390

National Registry For Patients With HS



5 year study for adult and pediatric HS patients.  Various States.  Click below for info. NCT03289585

FDA Clinical Trials

Review all FDA trials here.  

UK Clinical Trials

See all UK clinical trials here.


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